Department of Veterans Affairs
Veterans Affairs research and development is focused on improving the lives of veterans and all Americans through health care discovery and innovation focusing on rehabilitation, mental health, prosthetics, pain management, and chronic diseases.
Nicotine metabolite as neurodegenerative disease therapeutic
Continine may play a role in boosting the efficacy of current drugs used for the treatment of Alzheimer’s, Parkinson’s and related neural diseases
Cell-penetrating antibody 3E10 as a transport vehicle to...
Enhanced or synergistic inhibition of the growth of tumor cells when multiple components of a regulatory pathway are targeted with more than one therapeutic...
Lactate trapping complex as a cancer diagnostic and...
Tumoricidal compositions which are less harmful to cells having mitochondria with the capacity to shuttle pyruvate than the subset of cancer cells that exclusively...
Leishmaniasis diagnostic test
Rapid, and relatively inexpensive means of detecting, quantifying, and determining the species of Leishmania in clinical or epidemiologic samples
Portable, non-invasive testing device for emerging inner ear...
Identification and monitoring of ototoxic-induced hearing loss and sensorineural damage
Reactivating silenced cardiac gene expression as a treatment...
Phenylbutyrate, in combination with an ACE inhibitor reestablishes normal cardiac gene transcription to induce adult proteins and regress ventricular enlargement due to heart failure
Extendable wand mouthstick stylus
Telescoping device can be extended or retracted based on bite signals greatly enhancing the range and utility of the instrument
Improved urinary catheter that eliminates tissue damage
Increases patient comfort and decreases the chance of infection by lowering the risk of tissue damage and bacterial transport
Collapsible wheelchair with offset push rim for improved...
Decoupling of the push rim and drive wheels allows for optimal positioning of the user, enables gearing for improved locomotion, and creates better options...
Alzheimer’s and dementia treatment with CHP-Zinc formulation
Formulation decreases Aβ levels, increases insulin degrading enzyme activity, and enhances learning and memory in an AD mouse model
Imaging agent to diagnose impaired intestinal bile acid
This trifluorinated bile acid analogue is useful as an imaging probe, diagnostic agent, and contrast agent and is resistant to bacterial deconjugation